Vildagliptin anti-diabetic agent

Vildagliptin anti-diabetic agent [NBP2-62759] - Chemical structure of Vildagliptin, a Antidiabetic Agent. CAS #: 274901-16-5 . Molecular Formula: C17H25N3O2. Molecular Weight: 303.4 g/mol.

• Applications: IP

Vildagliptin anti-diabetic agent Summary

• Description: Anti-diabetic agent
  Purity: >98% (HPLC); NMR (conforms)
  CAS No.: 274901-16-5
  Molecular Formula: C₁₇H₂₅N₃O₂
  Molecular Weight: 303.4
  Source: Synthetic
  Appearance: White powder
  PubChem ID: 11077541

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
• Application Notes: White powder. May be dissolved in DMSO (45 mg/mL); or DMF (20 mg/mL); or ethanol (20 mg/mL).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Notes

Signal Word: Warning GHS Classifcation: GHS07 Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity - Single exposure, category 3 Hazard statement(s):
H302 H315 Causes skin irritation.
H319 Causes serious eye irritation.
H335 May cause respiratory irritation.

Precautionary statement(s): P301 + P312 + P330-P305 + P351 + P338

Background

Vildagliptin is a potent inhibitor of dipeptidyl peptidase IV (DPP IV), an enzyme that cleaves glucagon-like peptide 1 (GLP-1) (1). Delaying the degradation of GLP-1 extends the action of insulin and suppresses the release of glucagon which results in reduction in elevated blood glucose levels (hyperglycemia) (2). It is a clinically useful antidiabetic agent.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Support products are guaranteed for 6 months from date of receipt.