Toxoplasma Gondii P30 Antibody (P30/3)

• Reactivity: Pz
• Applications: WB, ELISA
• Clone: P30/3
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

Toxoplasma Gondii P30 Antibody (P30/3) Summary

• Immunogen: Native Toxoplasma Gondii P30 (purified).
• Specificity: Reacts with Toxoplasma Gondii P30 membrane protein
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: The end point titer in an indirect ELISA has been found to be 1/2,000,000 using purified Toxoplasma Gondii P30 as the coating antigen.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2)
• Preservative: 0.09% Sodium Azide
• Purity: Protein G purified

Alternate Names for Toxoplasma Gondii P30 Antibody (P30/3)

• p30
• SAG1 protein
• SAG1

Background

Toxoplasma is a crescent shaped sporozoan that lives as an intracellular parasite in various tissues of many vertebrates and completes its life cycle in a single host. Its life cycle includes two phases called the intestinal (or enteroepithelial) and extraintestinal phases. The intestinal phase produces oocysts and occurs only in cats, wild as well as domesticated. The extraintestinal phase occurs in all infected animals including cats, and produces tachyzoites (actively proliferating trophozoites) and eventually, bradyzoites (slowly growing trophozoites) or zoitocysts. Infection due to Toxoplasma gondii occurs in pregnant women where a variable degree of immunosuppression may exist or in patients receiving immunosuppressive drug therapy. Toxoplasma infects tissue of the GI tract where an active infection is accompanied by fever and enlargement of the spleen. Symptoms of toxoplasmosis are generally mild but severe infection of lymph nodes may occur. Congenital toxoplasmosis, in which the maternal infection is transmitted during pregnancy, can produce blindness or mental retardation in the newborn.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.