Thyroxine Antibody (BGN/098/281)

Product Discontinued

Thyroxine Antibody (BGN/098/281) Summary

• Immunogen: Synthetic thyroxine conjugated to Bovine Serum Albumin
• Localization: Secreted
• Specificity: This product recognises Thyroxine, also known as T4, the major hormone secreted by the follicular cells of the thyroid gland. Thyroxine's main role is to regulate metabolic processes in the body such as heart rate, along with Triiodothyronine (T3). T4 is involved in thyroid disorders, such as hyperthyroidism and hypothyroidism. It also shows low levels of reactivity with biologically inactive rT3 (approximately 10%) and minimal reactivity with T3 (approximately 1.5%).
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000

Reactivity Notes

Human. Not yet tested in other species.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Phosphate Buffered Saline
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Protein A purified

Alternate Names for Thyroxine Antibody (BGN/098/281)

• T4

Background

Hormone produced by the thyroid glands to regulate metabolism by controlling the rate of oxidation in cells. Cases of hypothyroidism, where the gland is insufficiently active, can be treated by administration of thyroxine or a combination of thyroxine and triiodothyronine.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.