Thromboxane B2 Parameter Assay Kit

• Reactivity: All-Multi
• Applications: ELISA
• Conjugate: Biotin

Thromboxane B2 Parameter Assay Kit Summary

• Background: The Parameter TXB₂ Immunoassay is a 3.5 hour competitive enzyme immunoassay designed to measure TXB₂ in cell culture supernates, serum, plasma, and urine.
• Specificity: Measures TXB₂ levels in various samples
• Source: N/A
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Thromboxane B2 Parameter Assay Kit

• Thromboxane B2
• TXB2

Background

Thromboxane A2 (TXA2), is an eicosanoid involved in platelet aggregation, vasoconstriction, and reproductive functions. However, as TXA2 is rapidly degraded in vivo, TXA2 production is typically examined by assaying the more stable Thromboxane B2 (TXB2) or 11-dehydro-TXB2 (11-d-TXB2) derivatives. Levels of these metabolites are helpful markers in the study of diseases including liver cirrhosis, cystic fibrosis, mastocytosis, systemic lupus erythematosus, thrombosis diseases, and others.

⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for Thromboxane B2 (KGE011)(14)

Publications using KGE011

• Lee, GH;Lee, SY;Chae, JY;Kim, JW;Kim, JH;Jeong, HG; Antarctic Krill Oil from Euphausia superba Ameliorates Carrageenan-Induced Thrombosis in a Mouse Model International journal of molecular sciences 2023-12-13 [PMID: 38139268] (Mouse)
• EHT Lim, APJ Vlaar, LDJ Bos, LA van Vught, AMT Boer, RWG Dujardin, M Habel, Z Xu, MC Brouwer, D van de Bee, S de Bruin, Amsterdam Anti-C5a antibody vilobelimab treatment and the effect on biomarkers of inflammation and coagulation in patients with severe COVID-19: a substudy of the �phase 2�PANAMO trial Respiratory Research, 2022-12-24;23(1):375. 2022-12-24 [PMID: 36566174] (Human)
• KA Wickham, LB Nørregaard, MH Lundberg S, SS Cheung, Y Hellsten High-Intensity Exercise Training Improves Basal Platelet Prostacyclin Sensitivity and Potentiates the Response to Dual Anti-Platelet Therapy in Postmenopausal Women Biomolecules, 2022-10-17;12(10):. 2022-10-17 [PMID: 36291709] (Human)
• P Sundaravad, R Christophe, N Ramanujam, SR Chandra Serum thromboxane B2 but not soluble P-selectin levels identify ischemic stroke patients with persistent platelet reactivity while on aspirin therapy Thrombosis Research, 2021-10-28;208(0):92-98. 2021-10-28 [PMID: 34742142] (Human)
• JJ Shi, HF Liu, T Hu, X Gao, YB Zhang, WR Li, Q Wang, SJ Zhang, D Tang, YB Chen Danggui-Shaoyao-San improves cognitive impairment through inhibiting O-GlcNAc-modification of estrogen alpha receptor in female db/db mice Journal of ethnopharmacology, 2021-08-23;281(0):114562. 2021-08-23 [PMID: 34438027] (Mouse)
• X Zhao, J Li, Y Meng, M Cao, J Wang Treatment Effects of Jinlingzi Powder and Its Extractive Components on Gastric Ulcer Induced by Acetic Acid in Rats Evid Based Complement Alternat Med, 2019-01-03;2019(0):7365841. 2019-01-03 [PMID: 30719066] (Rat)
• Y Nakano, Y Nakatani, M Takami, Y Taniyama, S Arima Diverse associations between oxidative stress and thromboxane A2 in hypertensive glomerular injury Hypertens. Res., 2018-12-13;0(0):. 2018-12-13 [PMID: 30542084] (Rat)
• TA da Costa B, D de Oliveir, AT de Carvalh, NR da Costa F, DF Barreto-Vi, F Cunha Jáco, OM Barth, RMR Nogueira, PC da Costa N, DC de Souza M, EL de Azeredo, PV Damasco, RV da Cunha, LM de-Oliveir Different aspects of platelet evaluation in dengue: measurement of circulating mediators, ability to interact with the virus, the degree of activation and quantification of intraplatelet protein content Virus Res., 2018-09-30;0(0):. 2018-09-30 [PMID: 30282001] (Human)
• J Gubensek, K Strobl, S Harm, R Weiss, T Eichhorn, J Buturovic-, V Weber, J Hartmann Influence of citrate concentration on the activation of blood cells in an in vitro dialysis setup PLoS ONE, 2018-06-13;13(6):e0199204. 2018-06-13 [PMID: 29898003] (Human)
• D Gogoi, N Arora, B Kalita, R Sarma, T Islam, SS Ghosh, R Devi, AK Mukherjee Anticoagulant mechanism, pharmacological activity, and assessment of preclinical safety of a novel fibrin(ogen)olytic serine protease from leaves of Leucas indica Sci Rep, 2018-04-18;8(1):6210. 2018-04-18 [PMID: 29670183] (Human)
• A Chabert, P Damien, PO Verhoeven, F Grattard, P Berthelot, F Zeni, L Panicot-Du, S Robert, F Dignat-Geo, MA Eyraud, B Pozzetto, B Payrastre, F Cognasse, O Garraud, H Hamzeh-Cog Acetylsalicylic acid differentially limits the activation and expression of cell death markers in human platelets exposed to Staphylococcus aureus strains Sci Rep, 2017-07-17;7(1):5610. 2017-07-17 [PMID: 28717145] (Human)
• Directed transport of neutrophil-derived extracellular vesicles enables platelet-mediated innate immune response Nat Commun, 2016-11-15;7(0):13464. 2016-11-15 [PMID: 27845343] (Mouse)
• Anti-tumor and Anti-angiogenic Effects of Aspirin-PC in Ovarian Cancer Mol Cancer Ther, 2016-09-16;0(0):. 2016-09-16 [PMID: 27638860] (Mouse)
• Herrera-Garcia A, Dominguez-Luis M, Arce-Franco M, Lopez-Fernandez J, Feria M, Barreiro O, Sanchez-Madrid F, Diaz-Gonzalez F In vivo modulation of the inflammatory response by nonsteroidal antiinflammatory drug-related compounds that trigger L-selectin shedding. Eur J Immunol, 2012-10-26;43(1):55-64. 2012-10-26 [PMID: 22975861] (Mouse)