TAG-72 Antibody (IHC072)

Immunohistochemistry-Paraffin: TAG-72 Antibody (IHC072) [NBP2-75986] - Staining of TAG-72 Antibody (IHC072) in colon.

Product Discontinued

TAG-72 Antibody (IHC072) Summary

• Immunogen: Recombinant Human TAG-72
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:100 - 1:200
  • Immunohistochemistry-Paraffin 1:100 - 1:200
• Application Notes: Visualization of the antigen present in tissue sections is accomplished in a multi-step immunohistochemical staining process, in conjunction with a horseradish peroxidase (HRP) or alkaline phosphatase (AP) linked detection system. Positive control: Lung Adenocarcinoma. The 7mL size is a pre-diluted size and no additional dilutions are required before using this item for the intended application.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: Tris Buffer, pH 7.3 - 7.7, with 1% BSA
• Preservative: 0.1% Sodium Azide
• Purity: Protein A purified

Alternate Names for TAG-72 Antibody (IHC072)

• CA 72-4
• Protein TAG-72
• tag 72
• tag-72 Protein TAG-72

Background

Tumor-associated glycoprotein (TAG-72) is an oncofetal antigen with properties of a mucin. About 60% of carcinoma patients express TAG-72 in their sera. Majority of human adenocarcinomas including colorectal, pancreatic, gastric, ovarian, endometrial, mammary, and non-small cell lung cancer display some cell populations that are positive for Ab-1 staining. Weak or no reactivity has been observed with most cell types of normal adult tissue excepting the secretory endometrium. Ab-1 is reportedly useful in distinguishing pulmonary adenocarcinomas (B72.3+) from pleural mesotheliomas (B72.3-).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.