Staphylococcus Aureus Antibody (11-248.2)

Product Discontinued

Staphylococcus Aureus Antibody (11-248.2) Summary

• Immunogen: UV inactivated Staphylococcus aureus cells.
• Specificity: This product is specific for Staphylococcus aureus. No reactivity is seen with Streptococcus sp., Mycoplasma sp., or Corynebacteria sp.
• Isotype: IgM
• Clonality: Monoclonal
• Host: Mouse
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Ascites
• Preservative: 0.1% Sodium Azide
• Purity: Unpurified

Alternate Names for Staphylococcus Aureus Antibody (11-248.2)

• S. aureus

Background

Staphylococcal enterotoxins represent a group of proteins, which are secreted by Staphylococcus aureus and cause the intoxication staphylococcal food poisoning syndrome. The illness characterised by high fever, hypotension, diarrhea, shock, and in some cases death. Their molecular masses range between 27 and 30 kDa. At present, seven enterotoxins are known, namely A, B, C1, C2, C3, D and E. Their amino acid sequences have been determined and it was shown that all are single chain polypeptides containing one disulfide bond formed by two half cystines located in the middle of the polypeptide chain, which form the so called cysteine loop. Enterotoxins are extremely potent activator of T cells, stimulating the production and secretion of various cytokines which mediate many of the toxic effects of these substances. Enterotoxins are Superantigens, inducing polyclonal T cell activation by binding to the TCR and to the alpha chain of the MHC II molecule simultaneously.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.