SARS Nucleocapsid Protein Antibody (18F629.1)

Product Discontinued

SARS Nucleocapsid Protein Antibody (18F629.1) Summary

• Immunogen: The antibody was developed by immunizing mice with a synthetic peptide corresponding to amino acids 354-370 (NKHIDAYKTFPPTEPKK-C) from the N (SARS Nucleocapsid) for the Human SARS coronavirus (Genbank accession no. YP_009724397.2)
• Predicted Species: SARS-CoV-2 (100%). Backed by our 100% Guarantee.
• Isotype: IgM
• Clonality: Monoclonal
• Host: Mouse
• Gene: N
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1: 1000

Reactivity Notes

Expected species cross reactivity based on immunogen sequence homology: COVID-19 (100%)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 0.2 ml PBS and 0.2% Gelatin
• Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Protein G purified

Alternate Names for SARS Nucleocapsid Protein Antibody (18F629.1)

• COVID-19 nucleocapsid protein
• N protein
• N structural protein
• N
• NC
• Nucleocapsid protein
• Nucleoprotein
• Protein N
• SARS coronavirus N protein
• SARS coronavirus nucleocapsid protein
• SARS CoV N protein
• SARS CoV nucleocapsid protein
• SARS CoV
• SARS N protein
• SARS Nucleoprotein
• SARSCoV N protein
• SARSCoV nucleocapsid protein
• SARSCoV
• SARSCOV2 N protein
• SARS-COV-2 nucleocapsid protein
• SARS-COV-2 Nucleoprotein
• Severe acute respiratory syndrome

Background

It has recently been shown that SARS is caused by a human coronavirus. Human coronaviruses are the major cause of upper respiratory tract illness in humans, such as the common cold. Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The first step in coronavirus infection is binding of the viral spike protein, a 139-kDa protein, to certain receptors on host cells. The spike protein is the main surface antigen of the coronavirus. The most prominent protein in the culture supernatants infected with SARS virus is a 46 kDa nucleocapsid protein. This suggests that the nucleocapsid protein is a major immunogen that may be useful for early diagnostics.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: N