Saporin Peptide

Product Discontinued

Saporin Peptide Summary

• Description: A protein to Saporin.
• Immunogen: Saporin, whole molecule
• Localization: Accession Number: saporin
• Protein/Peptide Type: Peptide

Applications/Dilutions

• Dilutions:
  • ELISA 1:200 to 1: 2000
  • Immunocytochemistry/ Immunofluorescence 1:200 - 1:2000
  • Immunohistochemistry
  • Western Blot 1:200 to 1: 2000
• Application Notes: Immunohistochemistry, Immnunofluorescence, ELISA and Western Blot

Packaging, Storage & Formulations

• Storage: Store at -80C. Avoid freeze-thaw cycles.
• Buffer: Saporin may be reconstituted in the buffer of choice for example PBS.
• Preservative: No Preservative

Alternate Names for Saporin Peptide

• Common soapwort
• Saponaria officinalis

Background

Saporin is a ribosome-inactivating protein (RIP) of type I. This monomeric RNA N-glycosidase purified from seeds of the plant Saponaria officinalis also known as Soapwort, is capable of specific depurination of eukaryotic ribosomes thus arresting protein synthesis. No ligand has been identified in saporin hence its inability to transverse the cell membrane. Due to its toxicity and stability of the structure, saporin has proven extremely useful for construction of immunotoxins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.