Ricin Antibody (TFTB1)

Product Discontinued

Ricin Antibody (TFTB1) Summary

• Immunogen: Ricin B chain.
• Specificity: The antibody does not cross-react with the ricin A chain.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:10-1:2000

Reactivity Notes

Ricinus communis (Castor bean)

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Ascites
• Preservative: No Preservative
• Purity: Unpurified

Alternate Names for Ricin Antibody (TFTB1)

• Linker peptide
• Ricin A chain
• Ricin B chain
• Ricinus communis (Castor bean)
• rRNA N-glycosidase

Background

Ricin is a protein produced by the castor oil plant, Ricinus Communis. Ricin is a heterodimeric ribosome inhibiting protein. The ribosome inactivating protein called the A chain(RTA) and is linked by a disulphide bond to the B-chain(RTB), which is the binding lectin. Thus the ribosome inactivator is attached to a protein that can transport it into cells, where it is toxic. The total molecular weight is 66 000, with the A chain being 32 KDa and the B chain 34 KDa.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Uniprot:
  • P02879(Human)