Respiratory Syncytial Virus Antibody (2F7) [Alexa Fluor® 405]

Product Discontinued

Respiratory Syncytial Virus Antibody (2F7) [Alexa Fluor® 405] Summary

• Immunogen: Recombinant F protein
• Specificity: The mouse monoclonal recognizes 2 fusion proteins F0 (70 kDa) and F1 (48 kDa) subunits of the RSV present on RSV strains (Paramyxovirus 1, 2 & 3). No cross-reaction with other respiratory viruses.
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Respiratory Syncytial Virus Antibody (2F7) [Alexa Fluor® 405]

• Fusion glycoprotein F0
• Fusion glycoprotein F1
• Fusion glycoprotein F2
• RS virus
• RSV

Background

RSV (Respiratory Syncytial Virus) is a negative sense RNA paramyxovirus in which the major virus neutralization antigens are the glycoprotein (G) and the fusion (F) protein that mediate attachment and fusion to the host cell during virus infection, respectively. Other RSV proteins include the nucleocapsid protein (N) and the M2 protein. The two major subgroups of RSV are A and B with the A strain being more virulent and responsible for the majority of severe RSV infections. Respiratory syncytial virus infection is responsible for a large proportion of viral respiratory infections, and significant morbidity is associated with RSV infections. To date, few RSV vaccine candidates have shown promise with no human vaccine yet been proven safe and efficacious.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.