Rabbit IgG, Fc Native Protein


SDS-Page: Rabbit IgG, Fc Native Protein [NBP1-97061] - SDS-PAGE of Rabbit IgG F(c) Fragment. Lane M: 3 uL Opal Prestained Marker. Lane 1: Reduced Rabbit IgG Whole Molecule. Lane 2: Reduced Rabbit IgG F(ab) Fragment. ...read more

Product Details

Reactivity RbSpecies Glossary
Applications WB, ELISA, IHC, PAGE
1.1 mg/ml

Order Details

Rabbit IgG, Fc Native Protein Summary

A full-length protein corresponding to Rabbit IgG, Fc.

Source: Serum

Rabbit IgG F(c) fragment was prepared from normal serum by a multi-step process which includes delipidation, salt fractionation, ion exchange chromatography and papain digestion followed by chromatographic separation and extensive dialysis against the buffer stated above. Rabbit IgG F(c) fragment assayed by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum, anti-Rabbit IgG and anti-Rabbit IgG F(c). No reaction was observed against anti-Rabbit IgG F(ab')2 or anti-Papain.
Protein/Peptide Type
Native Protein
Ion exchange chromatography

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride pH 7.2
0.01% Sodium Azide
1.1 mg/ml
Ion exchange chromatography


Secreted as part of the adaptive immune response by plasma B cells, immunoglobulin G constitutes 75% of serum immunoglobulins. Immunoglobulin G binds to viruses, bacteria, as well as fungi and facilitates their destruction or neutralization via agglutination (and thereby immobilizing them), activation of the compliment cascade, and opsonization for phagocytosis. The F(c) fragment binds with very high affinity to the Fc receptor proteins on phagocytic leukocytes. When digested from the whole antibody molecule, the F(c) fragment no longer possesses the epitope recognition site. Rabbit IgG F(c) fragment is ideal for investigators in Immunology, Cancer, and Microbiology research.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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