Protocadherin-19 Antibody (921614) [Unconjugated]

SH-SY5Y human neuroblastoma cell line was stained with Mouse Anti-Human Protocadherin-19 Monoclonal Antibody (Catalog # MAB8626, filled histogram) or isotype control antibody (MAB0041, open histogram), followed by Allophycocyanin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0101B).

Jurkat cells were stained with Mouse Anti-Human Protocadherin-19 Monoclonal Antibody (Catalog # MAB8626, filled histogram) or isotype control antibody (Catalog # MAB0041, open histogram), followed by Phycoerythrin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0102B). View our protocol for Staining Membrane-associated Proteins.

Product Discontinued

Protocadherin-19 Antibody (921614) [Unconjugated] Summary

• Immunogen: HEK293 human embryonic kidney cell line transfected with human Protocadherin-19
  Met1-Ser678
  Accession # Q8TAB3
• Specificity: Detects human Protocadherin-19 in direct ELISA and flow cytometry.
• Source: N/A
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: PCDH19
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry 0.25 ug/10^6 cells

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Reconstitution Instructions: Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Protocadherin-19 Antibody (921614) [Unconjugated]

• EFMR
• EFMR;EIEE9;KIAA1313;PCDH19
• EIEE9
• PCDH19
• Protocadherin19
• Protocadherin-19

Background

Protocadherin 19 (PCDH19) is a d2-group member of the of the protocadherin subfamily, cadherin family of molecules.  PCDH19 is thought to be a calcium-dependent protein primarily expressed in the brain.  The protein is also known as EFMR (Epilepsy Female-restricted with Mental Retardation).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PCDH19
• Uniprot:
  • Q8TAB3()