Progesterone R B/NR3C3 Antibody (H5344) [Unconjugated]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IP, ELISA
Clone
H5344
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Suitable Sample Type
23015

Order Details

Progesterone R B/NR3C3 Antibody (H5344) [Unconjugated] Summary

Immunogen
Recombinant human Progesterone R B/NR3C3
aa 2-99
Specificity
This antibody specifically reacts with human PR isoform B and cross-reacts with mouse and rat PR isoform B. It does not cross-react with human PR isoform A. Not yet tested in other species.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
PGR
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Immunohistochemistry 5-15 ug/mL
  • Immunoprecipitation
  • Direct ELISA

Packaging, Storage & Formulations

Storage
This antibody is stable for greater than six months when held at -20 °C in a manual defrost freezer or at -70 °C. Upon thawing, the antibody can be stored at 2-8 °C for at least 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Buffer
A liquid formulation in physiologic saline with 0.1% NaN3.
Preservative
0.1% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Progesterone R B/NR3C3 Antibody (H5344) [Unconjugated]

  • PGRB
  • Progesterone R B
  • Progesterone RB

Background

Progesterone Receptor (PR; NR3C3) is a member of the Steroid Receptor superfamily. PR binds Progesterone. It is expressed in the uterus, ovary, vagina, fallopian tubes and breast. PR plays a central role in diverse reproductive events associated with the establishment and maintenance of pregnancy, alveolar development in the breast, and sexual behavior. Two isoforms of this receptor have been identified, PR-A and PR-B, 94 and 114 kDa in size, respectively. It has been shown that PR-A and PR-B isoforms can form homodimers as well as heterodimers.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PGR