Pneumolysin Antibody (1F11) [DyLight 405]

Product Discontinued

Pneumolysin Antibody (1F11) [DyLight 405] Summary

• Immunogen: Pneumolysin from at least 9 different types of pneumococcal strains
• Specificity: Reacts specifically with Pneumolysin from at least 9 different types of pneumococcal strains when tested by SDS-PAGE and WB. The tested pneumococcal types were 5, 6A, 11A, 11F, 12B, 15F, 19A, 25F and 35A.
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Background

Pneumolysin (pneumococcal hemolysin) is an intracellular protein produced by all strains of S. pneumoniae (1) and is a cytoplasmic cholesterol-dependent cytolysin forming large pores in cholesterol containing membranes and are therefore cytotoxic to mammalian cells (2). The molecular weight of Pneumolysin is approximately 53 kDa.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.