Plumbagin (IL17 Inhibitor)

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Plumbagin (IL17 Inhibitor) [NBP2-26242]
Plumbagin (IL17 Inhibitor) [NBP2-26242] - Evaluation of inhibitor activity on induction of IL-17A. IL-17A Prom/ LUCPorter™ HEK 293 cells were plated in 96-well white plates at 5 x 10^4 cells/well for 16 h. Cells ...read more
Plumbagin (IL17 Inhibitor) [NBP2-26242] - Inhibitor suppresses IL-17A production in human PBMC stimulated with anti-CD3/CD28. Perpheral blood mononuclear cells (PBMC) were stimulated with anti-CD3/CD28 in the presence ...read more

Product Details

Summary

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Plumbagin (IL17 Inhibitor) Summary

Immunogen
Plumbagin from Plumbago indica
Empirical Formula (Hill Notation) C11H8O3
Molecular Weight 188.18
PubChem Substance ID 24898833
CAS Number 481-42-5

Applications/Dilutions

Application Notes
Exhibits cytotoxicity in rodent models of carcinogenesis and carcinoma; has antifungal, antiviral, and antibacterial action.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.

Alternate Names for Plumbagin (IL17 Inhibitor)

  • 5-Hydroxy-2-methyl-1,4-naphthoquinone
  • C11H8O3
  • Plumbago indica

Background

Plumbagin exhibits cytotoxicity in rodent models of carcinogenesis and carcinoma. Plumbagin is a unique suppressor of CXCR4 expression making in useful in studies of cancer metastasis. Plumbagin has antifungal, antiviral, and antibacterial action.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Inhibitors are guaranteed for 1 year from date of receipt.

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Additional Plumbagin Products

Plumbagin NBP2-26242

Blogs on Plumbagin.

Plumbagin: A Natural Chemotherapeutic
Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) is a toxin, named after the plant genus Plumbago from which it was first isolated in 1968 (1). Since its discovery there have been a wide variety of publications describing its effects on fertility, hy...  Read full blog post.

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