Phenylalanine Antibody

Product Discontinued

Phenylalanine Antibody Summary

• Immunogen: Chemical / Small Molecule by a Glutaraldehyde linker.
• Specificity: Using a conjugate Phenylalanine-Glutaraldehyde-(Pc), antibody specificity was performed with an ELISA test by competition experiments with the following compounds: Phenylalanine-Glutaraldehyde-BSA (1:1), Tyrosine-Glutaraldehyde-BSA (1:> 50,000), L-DOPA-Glutaraldehyde-BSA (1:> 50,000). Ratios calculated as Phenylalanine-Glutaraldehyde-BSA concentration/ unconjugated or conjugated amino acids concentration at half displacement.
• Clonality: Polyclonal
• Host: Rabbit
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
• Application Notes: ELISA: use at a dilution of 1/2000 - 1/10000.Not tested in other applications.Optimal dilutions / concentrations should be determined by the end user.

Reactivity Notes

All Species.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: Whole antisera
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Unpurified
• Reconstitution Instructions: Please contact technical support for detailed reconstituion instruction.

Background

Phenylalanine is the most commonly found aromatic, essential amino acid. In a normal individual it is converted to tyrosine, which in turn is used to synthesise dopamine and norepinephrine (nerurotransmitters). Phenylalanine takes three differnt forms; L-, D- and DL-. The L- form is the most common and the type in which it is incorporated into the body's proteins. The D- form acts as a painkiller and the DL- a combination of the two. Phenylalanine is used to elevate mood as it is involved with the nervous system, it can also aid memory and learning and can been used as an appetite suppressant. Treatment with phenylalanine can be benificial in sufferes of Parkinson's disease, to treat depression and the D form may also be helpful in the treatment of chronic pain in both osteo-arthritis and rheumatoid arthritis. Deficiency is rare but symptoms may include lethargy, edema, weakness, skin lesions as well as liver damage and slow growth.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.