Oligodendrocyte Marker O4 Antibody (O4) [NL637]

Product Discontinued

Oligodendrocyte Marker O4 Antibody (O4) [NL637] Summary

• Additional Information: Clone UCHT1 was used by HLDA to establish CD designation
• Specificity: Detects human, mouse, rat, and chicken Oligodendrocyte Marker O4.
• Isotype: IgM
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.
• Buffer: Supplied in a saline solution containing BSA and Sodium Azide.
• Preservative: Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

Oligodendrocytes are myelinating cells in the central nervous system (CNS) and form the myelin sheath of axons to support rapid nerve conduction. Oligodendrocyte Marker O4 is an antigen on the surface of oligodendrocyte progenitors (1, 2). It has been commonly used as the earliest recognized marker specific for the oligodendroglial lineage (3-8).

1. Schachner, M. et al. (1981) Dev. Biol. 83:328.
2. Bansal, R. et al. (1989) J. Neurosci. Res. 24:548.
3. Bansal, R. and Pfeiffer, S.E. (1989) Proc. Natl. Acad. Sci. USA 86:6181.
4. Gard, A. et al. (1995) Dev. Biol. 167:596.
5. Reynolds, R. and Hardy, R. (1997) J. Neurosci. Res. 47:455.
6. Ono, K. et al. (1997) J. Neurosci. Res. 48:212.
7. Pang, Y. et al. (2000) J. Neurosci. Res. 62:510.
8. Cai, Z. et al. (2001) Brain Res. 898:126.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.