| Reactivity | All-MultiSpecies Glossary |
| Clone | 306507 |
| Clonality | Monoclonal |
| Host | Mouse |
| Conjugate | Alexa Fluor Plus 488 |
| Specificity | Detects Nitrotyrosine adducts on proteins in Western blots. It does not cross-react with phosphotyrosine or 4‑hydroxynonenal adducts. Unfixed cells, tissues, and proteins can be treated with Peroxynitrite (Catalog # AR006) for use as positive controls with this antibody. |
| Isotype | IgG3 |
| Clonality | Monoclonal |
| Host | Mouse |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
| Storage | Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied |
| Buffer | Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide. |
3-Nitrotyrosine is formed when tyrosine is reacted with peroxynitrite. Since peroxynitrite is formed from nitric oxide and superoxide anion, nitrotyrosine adducts on proteins have been used as markers of oxidative cellular damage and macrophage activation. Elevated nitrotyrosine immunoreactivity has been found in inflammation, osteoarthritis, neurodegenerative diseases, and ischemic damage to the heart and brain.
Secondary Antibodies |
Isotype Controls |
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