NDM-1 Antibody [FITC]

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-77688F
    • Availability
      Product Discontinued

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NDM-1 Antibody [FITC] Summary

Immunogen
A synthetic peptide made to a C-terminal region of the E. coli bla-NDM-1 protein (within residues 100-158). [NCBI BAJ10873]
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 1:10 - 1:500
Application Notes
This NDM1 antibody is useful for Western blot where a band is seen ~12 kDa in recombinant protein. Note: This enzyme may form multimers.

Reactivity Notes

Bacteria.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Background

New Delhi metallo-beta-lactamase is an enzyme that predisposes bacteria to become antibiotic resistant. In Pakistan, multi-drug resistant bacteria are blamed for a higher than usual incidence of hospital infections. NDM1 has an interesting conformational design, in that it has a large active site which allows it to react with multiple substrates, and which changes distinctly after substrates bind to it. Therapies against NDM1 in tandem with antibiotic therapies are being postulated as the best potential defense against antibiotic resistance. However, the ability to identify NDM1 prevalence is also critical. Identification of colonized individuals by immunodetection assays could be a critical step in isolation and treatment.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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