NC1.1 Antibody (IC4) [PE]

Product Discontinued

NC1.1 Antibody (IC4) [PE] Summary

• Immunogen: Spleen cells from CBA mice
• Specificity: NB100-64244 recognizes an alloantigen designated NC1.1 expressed by murine natural cytotoxic cells. (NC1.1 is a 45kD cell surface antigen). Natural cytotoxic cells represent a small subset of cells with cytotoxic activity against certain tumour cells in functional assays. The IC4 monoclonal antibody has been shown to block substantially NC cells activity in vivo and in vitro. NB100-64244 recognizes the NC1.1 alloantigen in CBA, C57BL/6, BALB/c and NZB mice, but not in CE or DBA/2 mice.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1:10-1:1000

Reactivity Notes

Cross reacts with Mouse.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS (pH 7.4)
• Preservative: 0.09% Sodium Azide
• Concentration: LYOPH
• Purity: Protein G purified
• Reconstitution Instructions: Reconstitute with 1.0 ml distilled water.

Alternate Names for NC1.1 Antibody (IC4) [PE]

• NC1.1 alloantigen

Background

NC1.1 is an alloantigen expressed by murine natural cytotoxic cells. It is a 45kD cell surface antigen. Natural cytotoxic cells represent a small subset of cells with cytotoxic activity against certain tumor cells in functional assays. NC1.1 monoclonal antibody has been shown to block substantially NC cells' activity in vivo and in vitro.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.