Recombinant Bacterial Mycobacterium Tuberculosis ESAT6 His Protein

Images

 
SDS-Page: Recombinant Mycobacterium Tuberculosis ESAT6 Protein [NBP1-99045] - 3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain

Product Details

Summary
Reactivity BaSpecies Glossary
Applications PAGE
Concentration
0.5 mg/ml

Order Details

Recombinant Bacterial Mycobacterium Tuberculosis ESAT6 His Protein Summary

Description
A recombinant protein with a C-Terminal His-tag and corresponding to the amino acids 1-95 of Mycobacterium tuberculosis Mycobacterium Tuberculosis ESAT6

Source: Baculovirus

Amino Acid Sequence: ADPMTEQQWN FAGIEAAASA IQGNVTSIHS LLDEGKQSLT KLAAAWGGSG SEAYQGVQQK WDATATELNN ALQNLARTIS EAGQAMASTE GNVTGMFAHH HHHH

Source
Baculovirus
Protein/Peptide Type
Recombinant Protein
Purity
>90%, by SDS-PAGE
Endotoxin Note
< 1.0 EU per 1 microgram of protein (determined by LAL method)

Applications/Dilutions

Dilutions
  • SDS-Page
Theoretical MW
11 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publications using
NBP1-99045 in the following applications:

Reactivity Notes

Mycobacterium tuberculosis

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20 mM Tris-HCl buffer (pH 8.0), 10% glycerol
Preservative
No Preservative
Concentration
0.5 mg/ml
Purity
>90%, by SDS-PAGE

Alternate Names for Recombinant Bacterial Mycobacterium Tuberculosis ESAT6 His Protein

  • 6 kDa early secretory antigenic target ESXA
  • 6 kDa early secretory antigenic target
  • ESAT 6
  • esaT6
  • ESXA

Background

ESAT6, the 6 kDa early secretory antigenic target of Mycobacterium tuberculosis, is a secretory protein and potent T cell antigen. ESAT6 has been shown to directly bind to the TLR2 receptor, inhibiting downstream signal transduction. Recently it was shown that ESAT6 is very potential as diagnostic for differentiation between the mycobacterial infection and BCG vaccination. Recombinant Mycobacterium tuberculosis CDC1551 ESAT6 protein, fused to His-tag at C-terminus, was expressed in Baculovirus and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Publications for Mycobacterium Tuberculosis ESAT6 Recombinant Protein (NBP1-99045)(3)

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