Mumps Virus Native Protein

• Reactivity: V-Vi
• Applications: ELISA

Mumps Virus Native Protein Summary

• Description: Native mumps virus, Enders strain, cultured in BSC-1 cells.
  
  

  Source: Virus

  Amino Acid Sequence: UniProt P21277

  Instructions For Use:

  Product should be sonicated immediately before use to ensure the preparation is uniform. The product may be used in a variety of immunoassay formats or may be further purified to meet the requirements of a particular assay format.

• Preparation Method: Mumps virus, Enders strain, cultured in BSC-1 cells. Optimally infected cells are harvested, disrupted by sonication in culture medium and subjected to low speed centrifugation. The supernatant from the infected culture is concentrated by crossflow ultrafiltration. The antigen preparation is inactivated using gamma radiation, which primarily damages viral genetic material.
• Protein/Peptide Type: Native Protein

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: Antigenic activity is 51.1% of internal reference batch

Packaging, Storage & Formulations

• Storage: Store at -70C. Avoid freeze-thaw cycles.
• Buffer: Inactivated Mumps virus - liquid. Culture medium 1969B
• Preservative: No Preservative

Background

Mumps virus is a member of the Paramyxoviridae family and is the causative agent of mumps. Mumps is most typically characterised by painful swelling of the salivary glands and fever. In some adult men, the virus might also infect the testicles, rarely causing sterility. The virus is spread by airborne droplets from the nose or throat and can have an incubation period of up to three weeks. Infected individuals are contagious from approximately 6 days before until about 9 days after the onset of symptoms. The disease is self-limiting and treatment involves controlling specific symptoms. An effective vaccine exists and may be given separately or as part of the MMR vaccine.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Publications for Mumps Virus Native Protein (NBP2-62509)(1)

Publication using NBP2-62509

• Zhou Y, Shen H, Wu M et al. Pharmacology, pharmacokinetics, and toxicity characterization of a novel anti-CD73 therapeutic antibody IBI325 for cancer immunotherapy International journal of biological macromolecules 2022-12-29 [PMID: 36587633] (ELISA)

Bioinformatics

• Uniprot:
  • P21277(Virus)