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MSC 2032964A Inhibitor

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Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB5641
    • Availability
      Product Discontinued

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MSC 2032964A Inhibitor Summary

Description
Biological Activity
Potent and selective ASK1 inhibitor (IC50 = 93 nM). Selective for ASK1 over a panel of 210 kinases. Blocks LPS-induced ASK1 and p38 phosphorylation in cultured mouse astrocytes. Suppresses neuroinflammation in a mouse EAE model. Orally bioavailable and brain penetrant.

Technical Data
M.Wt: 362.31
Formula: C16H13F3N6O
Solubility: Soluble to 20 mM in DMSO and to 10 mM in ethanol with gentle warming
Purity:>98 %
CAS No:1124381-43-6

Packaging, Storage & Formulations

Storage
Store at -20 °C.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Inhibitors are guaranteed for 1 year from date of receipt.

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