Mouse IL-18 BPd DuoSet ELISA, 5 Plate

• Reactivity: Mu
• Applications: ELISA
• Conjugate: Biotin

Mouse IL-18 BPd DuoSet ELISA, 5 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: Il18bp

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse IL-18 BPd DuoSet ELISA, 5 Plate

• IL18 BPd
• IL-18 BPd

Background

Interleukin 18 binding proteins are secreted glycoproteins which antagonize IL-18 activity by binding IL-18 and blocking its biological activity. Alternative splicing of the IL-18 BP gene produces at least four isoforms that differ in affinity for IL-18. The IL-18 BP isoforms a and c each contain one immunoglobulin (Ig)-like C2-type domain while isoforms b and d lack a complete Ig-like domain.

Publications for IL-18 BPd (DY122-05)(5)

Publications using DY122-05

• JT Clark, OE Weizman, DL Aldridge, LA Shallberg, J Eberhard, Z Lanzar, D Wasche, JD Huck, T Zhou, AM Ring, CA Hunter IL-18BP mediates the balance between protective and pathological immune responses to Toxoplasma gondii Cell Reports, 2023-02-23;42(3):112147. 2023-02-23 [PMID: 36827187] (Mouse)
• G Chenxu, D Xianling, K Qin, H Linfeng, S Yan, X Mingxin, T Jun, X Minxuan Fisetin protects against high fat diet-induced nephropathy by inhibiting inflammation and oxidative stress via the blockage of iRhom2/NF-&kappaB signaling International immunopharmacology, 2021-01-08;92(0):107353. 2021-01-08 [PMID: 33429334] (Mouse)
• T Zhou, W Damsky, OE Weizman, MK McGeary, KP Hartmann, CE Rosen, S Fischer, R Jackson, RA Flavell, J Wang, MF Sanmamed, MW Bosenberg, AM Ring IL-18BP is a secreted immune checkpoint and barrier to IL-18 immunotherapy Nature, 2020-06-24;0(0):. 2020-06-24 [PMID: 32581358] (Mouse)
• K Radulovic, CK Ayata, R Mak'Anyeng, K Lechner, P Wuggenig, B Kaya, P Hruz, M Gomez de A, P Broz, B Weigmann, JH Niess NLRP6 Deficiency in CD4 T Cells Decreases T Cell Survival Associated with Increased Cell Death J. Immunol., 2019-05-31;0(0):. 2019-05-31 [PMID: 31152078] (Mouse)
• Z Dong, Y Yuan Accelerated inflammation and oxidative stress induced by LPS in acute lung injury: ?nhibition by ST1926 Int. J. Mol. Med., 2018-03-19;0(0):. 2018-03-19 [PMID: 29568857] (Mouse)

Bioinformatics

• Gene Symbol: Il18bp