Mouse CD3+ T Cell, Mini Column Enrichment Kit Summary
Mouse T Cell Enrichment Columns are designed to prepare purified mouse T cell populations via high affinity negative selection. The resulting column eluate is a highly enriched T cell population with minimal depletion of T cell constituents. Features
- Available for human, mouse, and rat cells
- Purifies CD3+ T cells to 83 - 90%
- Based upon gravitational flow
- Simple procedure
- No specialized equipment required
Packaging, Storage & Formulations
Store at 4C. Do not freeze.
- 10X Column Buffer Concentrate
- Mouse T Cell Selection Columns
The T cell receptor (TCR)/CD3 complex consists of two variable antigen-recognition receptor chains (TCR-alpha/TCR-beta or TCR-gamma/TCR-delta) that are non-covalently linked to at least four different invariant chains: CD3 gamma, CD3 delta, CD3 epsilon, and the CD3 zeta chain that exists as either a homodimer or as a heterodimer with its splice-variant the CD3 eta chain. The CD3 complex functions to transduce intracellular signals during TCR antigen recognition. CD3 is expressed early in thymocyte development, and on a subset of NK cells. CD3 epsilon is one of at least three invariant proteins that associate with the variable antigen recognition chains of the T cell receptor and function in signal transduction.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Kits are guaranteed
for 6 months from date of receipt.
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