Methamphetamine Antibody

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Product Details

Summary
Reactivity All-NASpecies Glossary
Applications ELISA
Clonality
Polyclonal
Host
Sheep
Conjugate
Unconjugated
Concentration
5.0 mg/ml

Order Details

Methamphetamine Antibody Summary

Immunogen
Para-amino-metamphetamine conjugated to keyhole limpet hemocyanin
Specificity
NB100-62754 is specific for methamphetamine.
Isotype
IgG
Clonality
Polyclonal
Host
Sheep
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000

Reactivity Notes

Chemical

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.09% Sodium Azide
Concentration
5.0 mg/ml
Purity
Protein G purified

Alternate Names for Methamphetamine Antibody

  • METH

Background

Methamphetamine (METH) is closely related chemically to amphetamine (AMPH). METH is a potent central nervous system stimulant with additional peripheral sympathomimetic effects. METH and AMPH have been used clinically in the treatment of obesity, minimal brain dysfunction, narcolepsy, depression and to counter fatigue. They are also subjected to widespread abuse. METH is an indirect agonists. It causes the release of newly synthesized norepinephrine and dopamine and it blocks the re uptake of these transmitters from the synapse. This can lead to an increase in the concentration of catecholamines in the synapse as well as an overall increase in catecholaminergic activity in the brain. The mechanism of METH induced neurotoxicity for all monoaminergic cell types may lie primarily with the dopaminergic system in the striatum. It may also lie with the interaction between METH induced release of dopamine and its ability to inhibit monoamine oxidase.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Additional Methamphetamine Products

Array NB100-62754

Blogs on Methamphetamine.

Methamphetamine with HIV induces mitochondrial dysfunction and neuronal injury through oxidative stress
By Jamshed Arslan, Pharm. D., PhD. December 1 is the World AIDS Day. Despite the combination antiretroviral therapy, 10-25% of Human Immunodeficiency Virus (HIV)-positive individuals report neurocognitive impairm...  Read full blog post.

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