MagCellect™ Plus Human CD45+ Cell Isolation Kit

Product Discontinued

MagCellect™ Plus Human CD45+ Cell Isolation Kit Summary

• Description: The MagCellect Plus Human CD45+ Cell Isolation Kit is designed to isolate CD45 expressing cells via a positive selection principle. The resulting cell preparation is highly enriched with CD45+ cells. Typical purity of recovered CD45+ cells ranges from 80-95%.
• Kit Type: Isolation Kit
• Gene: PTPRC

Applications/Dilutions

• Dilutions:
  • Flow Cytometry

Packaging, Storage & Formulations

• Storage: Storage is content dependent.

Background

CD45 is a transmembrane protein tyrosine phosphatase. It is expressed at high levels on the cell surface of all nucleated hematopoietic cells and their precursors. Alternative splicing of CD45 mRNA results in the expression of several distinct isoforms that are differentially expressed in cells of different lineages and activation states. MagCellect technology is based on the use of ferrofluids or magnetic nanoparticles that have no magnetic memory (superparamagnetic) and behave like colloidal particles. This feature allows the ferrofluids to remain in solution without the need for mixing and additionally allows for efficient diffusion kinetics during the binding reaction. The proprietary manufacturing technology of MagCellect(TM) Ferrofluids generates particles with higher ligand binding capacity per mass compared to many other larger diameter magnetic particles.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Kits are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: PTPRC