LDL Uptake Assay Kit (Fluorometric) Summary
LDL Uptake Cell-Based Assay Kit is a tool for studying LDL uptake and regulation at the cellular level.
3 x 10^4 cells per well
Assay Kit (Fluorometric)
Packaging, Storage & Formulations
Storage of components varies. See protocol for specific instructions.
- Rabbit Anti-LDL Receptor Primary Antibody
- DyLightTM 488-Conjugated Goat Anti- Rabbit IgG Secondary Antibody
- LDL-DyLightTM 550
- Cell-Based Assay Blocking Solution
- Cell-Based Assay Fixative
This product is produced by and distributed for Abnova, a company based in Taiwan.
LDL is the major carrier of cholesterol in the blood, accounting for more than 60% of total plasma cholesterol. LDL is taken up by hepatic and extrahepatic tissues through receptor-mediated endocytosis triggered by apoB-100-LDL receptor interaction. The internalized LDL particle is transported to lysosomes where it is degraded to free cholesterol and amino acids. In humans, the liver is the most important organ for LDL catabolism and LDL receptor activity. In the liver, LDL can be regulated by pharmacologic intervention.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Kits are guaranteed
for 6 months from date of receipt.
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