LDL, MDA treated Antibody (5D8) - BSA Free

Product Discontinued

LDL, MDA treated Antibody (5D8) - BSA Free Summary

• Immunogen: Low-density lipoprotein purified from human plasma and treated with MDA and adsorbed onto aluminum hydroxide gel
• Specificity: Reacts with MDA-treated LDL but not with native LDL
• Isotype: IgG1 Lambda
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:8000
  • Western Blot 1:100-1:2000

Reactivity Notes

Chemical

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: 10mM Phosphate (pH 7.4) and 0.5M NaCl
• Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Protein A or G purified

Alternate Names for LDL, MDA treated Antibody (5D8) - BSA Free

• Low density lipoprotein
• MDA oxidized LDL
• MDA oxidized low density lipoprotein

Background

Low-density lipoprotein (LDL) is the carrier protein for cholesterol in the blood. LDL binds to its receptor on the capillary walls and thereby mediates the uptake and clearance of cholesterol from the circulation. In atherosclerotic lesions oxidatively modified LDL is found and oxidized LDL is specifically recognized and ingested by macrophages via scavenger receptor A and CD36. Oxidized LDL may be a marker of atherosclerosis but the precise changes in oxidized LDL are not well described. MDA-treated LDL appear to be different from LDL oxidized by other means.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.