KSHV ORF8 Antibody

Product Discontinued

KSHV ORF8 Antibody Summary

• Immunogen: Synthetic peptide, corresponding to amino acids sequence of KSHV ORF8.
• Specificity: KSHV ORF8
• Clonality: Polyclonal
• Host: Rabbit
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:1000
• Application Notes: Anti-KSHV ORF8 polyantibody recognizes specific in TPA-induced BCBL-1 cell lysate by the Western Blot. Determining optimal working dilutions by titration test.

Reactivity Notes

Human. Other species have not been tested.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Whole antisera
• Preservative: No Preservative
• Purity: Unpurified

Alternate Names for KSHV ORF8 Antibody

• Glycoprotein B-like; Human herpes virus 8; Kaposi and #039;s sarcoma herpes virus; Kaposi and #039;s sarcoma herpes virus

Background

Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma-(2)-herpesvirus subfamily and has been closely linked to the Kaposi's sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman's disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. KSHV ORF8 is a virion envelope-associated protein. Akula et al (2003) report it acts as a Glycoprotein B mediated signaling during virus entry. This Glycoprotein possesses the Arg-Gly-Asp (RGD) motif and utilizes alpha3beta1 integrin as one of the receptors for its entry into the target cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.