Mouse anti-Human IgG Fc Secondary Antibody (CH1)

Product Discontinued

Mouse anti-Human IgG Fc Secondary Antibody (CH1) Summary

• Immunogen: IgG from human serum.
• Specificity: Class-specific for human IgG. No allotype restriction. Fc-region specific - relatively high affinity. No cross-reactivity with human IgA, IgM, IgE.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Sandwich ELISA

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS, pH 7.4
• Preservative: 0.09% Sodium Azide
• Purity: Protein G purified

Background

Immunoglobulin G (IgG), is one of the most abundant proteins in human serum with normal levels between 8-17 mg/ml in adult blood. IgG is important for our defence against microorganisms and the molecules are produced by B lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Secondary Antibodies are guaranteed for 1 year from date of receipt.