HPV16 Antibody (CAMVIR-1)

Product Discontinued

HPV16 Antibody (CAMVIR-1) Summary

• Immunogen: BALB/C mice were immunized with recombinant HPV-16 L1 protein.
• Localization: Nuclear
• Specificity: NB120-3199 identifies type 16 of HPV and is suitable for staining of formalin-fixed, paraffin embedded tissues.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Purity: Ascites

Applications/Dilutions

• Dilutions:
  • Adhesion Blockade
  • Immunocytochemistry/ Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
• Application Notes: Immunofluorescence: assay dependent.Immunohistochemistry (formalin fixed paraffin embedded): use at a concentration of 1 - 2ug / ml for 30 min at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min.

Reactivity Notes

Human reactivity reported in scientific literature (PMID: 28383029).

Packaging, Storage & Formulations

• Storage: Store at 4C.
• Buffer: Ascites, containing less than 0.1% sodium azide
• Preservative: Sodium Azide
• Concentration: This product is unpurified. The exact concentration of antibody is not quantifiable.
• Purity: Ascites

Alternate Names for HPV16 Antibody (CAMVIR-1)

• Human Papilloma Virus Type 16

Background

L1 is a major capsid protein of type 16 human papilloma virus. Infection with specific types of HPV has been asso ciated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for HPV16 Antibody (NB120-3199)(1)

Publication using NB120-3199

• Kannan A, Hertweck KL, Philley JV et al. Genetic Mutation and Exosome Signature of Human Papilloma Virus Associated Oropharyngeal Cancer. Sci Rep 2017-04-06 [PMID: 28383029] (Human)