ERVK2 Antibody

Product Discontinued

ERVK2 Antibody Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: ERVK2 (AAB63112, 88 a.a. - 197 a.a.) partial recombinant protein with GST tag. PQGMLNSPTICQTFVAQVLQPVRDKFSDCYIIHYVDDILCAAETRDKLIDCYTFLQTEVANAGLTIASDKIQTSTPFHYLGMQVEERKIKPQKVEIRKDTLRTLNDFKNC
• Specificity: ERVK2 - endogenous retroviral sequence K(C4), 2
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: ERVK2
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
• Application Notes: It has been used for ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 50 % glycerol
• Preservative: No Preservative
• Purity: Unpurified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for ERVK2 Antibody

• HERV-K
• polymerase

Background

ERVK2 - endogenous retroviral sequence K(C4), 2

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for ERVK2 Antibody (H00002087-A01)(6)

Publications using H00002087-A01

• Dhillon P, Mulholland KA, Hu H et al. Increased levels of endogenous retroviruses trigger fibroinflammation and play a role in kidney disease development Nature communications 2023-02-02 [PMID: 36732547] (WB, Human)
  
  Details:
  Dilution used in WB 1:100
• Douville RN, Nath A., et al. Human Endogenous Retrovirus-K and TDP-43 Expression Bridges ALS and HIV Neuropathology. Front Microbiol 2017-10-11 [PMID: 29075249]
• Manghera M, Ferguson-Parry J, Lin R, Douville RN. NF-kappaB and IRF1 Induce Endogenous Retrovirus K Expression via Interferon-Stimulated Response Elements in Its 5' Long Terminal Repeat. J Virol 2016-10-15 [PMID: 27512062] (Human)
• Manghera M, Ferguson-Parry J, Douville RN. TDP-43 regulates endogenous retrovirus-K viral protein accumulation. Neurobiol Dis 2016-06-28 [PMID: 27370226]
• Douville R, Liu J, Rothstein J, Nath A. Identification of active loci of a human endogenous retrovirus in neurons of patients with amyotrophic lateral sclerosis. Annals of Neurology. 2010-01-01 [PMID: 21280084]
• Douville R, Liu J, Rothstein J et al. Identification of active loci of a human endogenous retrovirus in neurons of patients with amyotrophic lateral sclerosis. Annals of Neurology Nov 8 2010

Bioinformatics

• Gene Symbol: ERVK2
• Entrez:
  • 2087(Human)
• Uniprot:
  • AAB63112(Human)