ER-HR3 Antibody (ER-HR3) [DyLight 488]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, ICC/IF, IHC, IHC-Fr
Clone
ER-HR3
Clonality
Monoclonal
Host
Rat
Conjugate
DyLight 488

ER-HR3 Antibody (ER-HR3) [DyLight 488] Summary

Immunogen
Adherent F1 (CBAxBL) bone marrow stormal cells.
Specificity
NB100-64931 recognizes the murine antigen ER-HR3. ER-HR3 is a cell surface antigen which is expressed by Langerhans cells in epithelium, a subset of mature macrophages and dendritic cells that are located predominantly in haematopoietic and lymphoid organs. Initial studies of ER-HR3 demonstrated expression on peripheral blood monocytes but recent studies suggest that expression is actually very low. During foetal development, ER-HR3 positive cells are localised to haemapoietic islands and are often associated with erythroid progenitor cells. The functions of the ER-HR3 antigen have not been established but reports suggest that the antigen may be involved in adult erythropoiesis and in the regulation of the immune response. Clone ER-HR3 does not inhibit T cell proliferation in antigen-specific T-cell proliferation studies. Clone ER-HR3 recognizes two proteins of approximately 69kD and 55kD under non-reducing conditions.
Isotype
IgG2c
Clonality
Monoclonal
Host
Rat
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for ER-HR3 Antibody (ER-HR3) [DyLight 488]

  • Hematopoiesis related macrophage

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Allophycocyanin Labeled NB100-64931APC
DyLight 350 Labeled NB100-64931UV
DyLight 405 Labeled NB100-64931V
DyLight 680 Labeled NB100-64931FR
DyLight 755 Labeled NB100-64931IR
PE Labeled NB100-64931PE
PerCP Labeled NB100-64931PCP

Additional ER-HR3 Products

ER-HR3 NB100-64931G

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