EBNA1 Antibody

Product Discontinued

EBNA1 Antibody Summary

• Immunogen: Purified recombinant EBNA1
• Specificity: NB100-64546 recognizes the Epstein Barr nuclear antigen (EBNA-1) a protein which activates replication of the Epstein Barr viral genome and is not recognized by the cellular immune system. EBNA-1 is consistently expressed in EBV-associated malignancies. This antibody does not react with human lymphoid cells.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 1:10-1:2000

Reactivity Notes

Viral. Not yet tested in other species.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2)
• Preservative: 0.09% Sodium Azide
• Concentration: 4.0 mg/ml
• Purity: IgG purified

Alternate Names for EBNA1 Antibody

• BKRF1
• Epstein-Barr nuclear antigen 1
• HHV4gp098
• nuclear antigen EBNA1

Background

Epstein Barr virus (EBV) is a member of the herpesvirus family and one of the most common human viruses. Most people become infected with EBV during their lives. Primary infections usually results in infectious mononucleosis (glandular fever) but the virus can also lay dormant in B lymphocytes and when reactivated become associated with more serious disease such as Burkitt's lymphoma, nasopharyngeal carcinoma and Hodgkin's disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.