Diphtheria Toxin Antibody [Alexa Fluor™ Plus 488]

• Reactivity: Ba
• Applications: ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Alexa Fluor Plus 488

Diphtheria Toxin Antibody [Alexa Fluor™ Plus 488] Summary

• Immunogen: Purified diphtheria toxoid
• Specificity: This product reacts with the diphtheria toxin/toxoid. Diphtheria toxin is an exotoxin secreted by various strains of Corynebacterium diphtheriae that is the cause of Diphtheria. The active toxin is a single chain of 535 amino acids composed of 3 distinct structural/functional domains; and N-terminal ADP-ribosyltransferase (catalytic domain); a region which facilitates the delivery of the catalytic domain across the cell membrane (transmembrane domain) and the eukaryotic cell receptor binding domain.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Diphtheria Toxin Antibody [Alexa Fluor™ Plus 488]

• Diphtheria Toxin
• tox

Background

Corynebacterium diphtheriae is a gram-positive, nonmotile bacteria found in soil and animal feces. C. diphteriae infect the epithelial cells of the upper respiratory tract from where they produce and secrete a potent toxin. This toxin is absorbed and disseminated through lymph channels and blood to the susceptible tissues of the body.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.