Cysteinyl Leukotriene ELISA Kit (Colorimetric) Summary
|Standard Curve Range
78.1 - 2,500 pg/ml
Human Urine - 107.6%
Tissue Culture Media - 101.0%
ELISA Kit (Colorimetric)
Packaging, Storage & Formulations
- Assay buffer concentrate
- GxM Microtiter plate
- pNpp Substrate
- Stop solution
- Wash buffer concentrate
Leukotrienes are major products of 5-lipoxygenase metabolism of arachidonic acid. Leukotriene B4 (LTB4) stimulates leukocyte functions including lysosomal enzyme release, adhesion, and aggregation of polymorphonuclear leukocytes. LTB4 has been implicated as a potent mediator of inflammatory diseases and immunoregulation. The cysteinyl leukotrienes (LTC4, LTD4, and LTE4) are formed by addition of cysteine derivatives to LTA4. The conversion of LTA4 to LTC4 by the enzyme LTC4 synthase limits the rate of cysteinyl leukotriene formation. Cysteinyl leukotrienes are potent lipid mediators in inflammation, inducing smooth muscle contractions and increased capillary permeability.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed
for 6 months from date of receipt.
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