Complement Factor H Autoantibody (IgG) ELISA Kit (Colorimetric)

• Applications: ELISA, NULL
• Suitable Sample Type: Plasma, Serum
• Standard Curve Range: 3.9 to 250 AU/mL
• Sensitivity: 0.6 AU/mL

Complement Factor H Autoantibody (IgG) ELISA Kit (Colorimetric) Summary

• Description: Anti-CFH IgG (Human) ELISA Kit is a solid phase enzyme immunoassay for the quantitative measurement of IgG class autoantibodies against CFH.
• Standard Curve Range: 3.9 to 250 AU/mL
• Sensitivity: 0.6 AU/mL
• Assay Type: solid phase enzyme-linked immunosorbent assay
• Inter-Assay: CV% < 12.75%
• Intra-Assay: CV% < 7%
• Sample Volume: 100 uL
• Kit Type: ELISA Kit (Colorimetric)

Applications/Dilutions

• Dilutions:
  • ELISA
  • Quantification

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Complement Factor H Autoantibody (IgG) ELISA Kit (Colorimetric)

• CFH IgG

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Publications for Complement Factor H Autoantibody (IgG) ELISA Kit (KA1477)(11)

Publications using KA1477

• Selcuk Y, Ipek G, Nur C et al. Renal Biopsy Prognostic Findings in Children With Atypical Hemolytic Uremic Syndrome. Pediatr Dev Pathol. 2020-05-14 [PMID: 32406813]
• Fujisawa M, Yasumoto A, Kato H et al. The role of anti-complement factor H antibodies in the development of atypical haemolytic uremic syndrome: a possible contribution to abnormality of platelet function. Br J Haematol. 2019-12-26 [PMID: 31879952]
• Nakayama S, Hirashio S, Yorishima H et al. Atypical reduction of plasma ADAMTS13 activity by a non-IgG-type inhibitor in a patient with hemolytic uremic syndrome caused by Shiga toxin-producing Escherichia coli. CEN Case Rep. 2019-06-08 [PMID: 31177384]
• Tseng MH, Tsai JD, Tsai IJ et al. Whole-exome sequencing detects mutations in pediatric patients with atypical hemolytic uremic syndrome in Taiwan. Clin Chim Acta. 2019-03-21 [PMID: 30905589]
• Fidan K, Goknar N, Gulhan B et al. Extra-Renal manifestations of atypical hemolytic uremic syndrome in children. Pediatr Nephrol 2018-04-02 [PMID: 29610995]
• Fujisawa M, Kato H, Yoshida Y et al. Clinical characteristics and genetic backgrounds of Japanese patients with atypical hemolytic uremic syndrome. Clin Exp Nephrol 2018-03-06 [PMID: 29511899]
• Tseng M, Lin S, Wu C et al. Serum complement factor I is associated with disease activity of systemic lupus erythematosus. Oncotarget. 2018-02-02 [PMID: 29492211]
• Besbas N, Gulhan B, Soylemezoglu O et al. Turkish pediatric atypical hemolytic uremic syndrome registry: initial analysis of 146 patients. BMC Nephrol 2017-01-05 [PMID: 28056875]
• Yuksel S, Evrengul H, Ozcakar ZB et al. First-Line, Early and Long-Term Eculizumab Therapy in Atypical Hemolytic Uremic Syndrome: A Case Series in Pediatric Patients. Paediatr Drugs 2016-09-19 [PMID: 27646857]
• Zhang C, Zhang DF, Wu ZG et al. Complement factor H and susceptibility to major depressive disorder in Han Chinese. Br J Psychiatry 2016-03-03 [PMID: 26941266]
• Lee JM, Park YS, Lee JH et al. Atypical hemolytic uremic syndrome: a Korean pediatric series. Pediatr Int. [PMID: 25443527]

FAQs for Complement Factor H Autoantibody (IgG) ELISA Kit (KA1477). (Showing 1 - 2 of 2 FAQs).

1. I am looking for an ELISA kit to measure Auto-Factor H Antibodies in serum. Do you offer a kit suitable for this purpose?
   • We do carry one ELISA kit that has the description: Anti-CFH IgG (Human) ELISA Kit is a solid phase enzyme immunoassay for the quantitative measurement of IgG class auto-antibodies against CFH. The kit catalog number is KA1477. This kit has been tested with serum and plasma samples.
2. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.