Clostridium Botulinum Toxin A Antibody (24A29)

Product Discontinued

Clostridium Botulinum Toxin A Antibody (24A29) Summary

• Immunogen: amino acid region 1177-1195, C. botulinum toxin A heavy chain
• Specificity: Mouse Monoclonal Clostridium botulinum toxin A (24A29)
• Isotype: IgM
• Clonality: Monoclonal
• Host: Mouse
• Purity: IgM purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Western Blot 1:100-1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS (pH 7.4)
• Preservative: 0.09% Sodium Azide
• Purity: IgM purified

Alternate Names for Clostridium Botulinum Toxin A Antibody (24A29)

• Atx
• Bna
• BoNT/A
• Bontoxilysin A
• BotA
• BOTOX
• Botulinum neurotoxin type A
• Botulism A toxoid

Background

Clostridium botulinum neurotoxins are zinc-dependent proteases that block the release of acetylcholine from peripheral cholinergic nerve endings by targeting specific membrane proteins including synaptosomal-associated proteins (SNAP), vesicle-associated membrane proteins (VAMP), and syntaxins. Neurotoxin A is characteristically associated with human botulism and known to target and hydrolyse the 197-Gln-|-Arg-198 bond of SNAP-25.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

FAQs for Clostridium Botulinum Toxin A Antibody (NB100-73116). (Showing 1 - 1 of 1 FAQ).

1. May we ask if the concentration of the latest lots of NB100-73115 and NB100-73116 can be informed?
   • For product NB100-73115, our current stock of material (lot: 14/07-CB19-A33) is provided at 4.5mg/ml. For NB100-73116, the most current lot of this product would be provided at a concentration of 2.0mg/ml (Lot: 15/05-Cb19-A29).