Clostridium Botulinum E Toxoid Antibody (KBE42)

Product Discontinued

Clostridium Botulinum E Toxoid Antibody (KBE42) Summary

• Immunogen: C. botulinum E toxoid.
• Specificity: C. Botulinum E toxoid. There is no cross-reactivity with A and B toxoids in sandwich ELISA.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Western Blot 1:100-1:2000
• Application Notes: Part of an antibody pair recommended for sandwich ELISA. It is suggested NB100-73123 be used as the capture antibody while NB100-73124 is used for detection.

Reactivity Notes

Bacteria.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS (pH 7.4)
• Preservative: 0.09% Sodium Azide
• Purity: Protein G purified

Alternate Names for Clostridium Botulinum E Toxoid Antibody (KBE42)

• BoNT/E
• Bontoxilysin e
• Botulinum neurotoxin type e non toxic component
• Botulinum neurotoxin type e precursor
• Botulism E toxoid
• Ent120

Background

Clostridium botulinum E Toxoid acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase. It has a non-toxic component which is necessary to maintain toxicity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.