Clostridium Botulinum E Toxoid Antibody (11D4) [DyLight 594]

Product Discontinued

Clostridium Botulinum E Toxoid Antibody (11D4) [DyLight 594] Summary

• Immunogen: Clostridium botulinum type E toxoid adsorbed onto aluminum hydroxide gel
• Specificity: Specific for botulinum toxoid. No cross reactivity to type A and type F toxoids.
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Chemical

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Clostridium Botulinum E Toxoid Antibody (11D4) [DyLight 594]

• BoNT/E
• Bontoxilysin e
• Botulinum neurotoxin type e non toxic component
• Botulinum neurotoxin type e precursor
• Botulism E toxoid
• Ent120

Background

Clostridium botulinum E Toxoid acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase. It has a non-toxic component which is necessary to maintain toxicity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.