Clostridium botulinum D Toxoid Antibody - BSA Free

Product Discontinued

Clostridium botulinum D Toxoid Antibody - BSA Free Summary

• Immunogen: Clostridium botulinum D toxoid, formalin fixed.
• Specificity: This product recognizes C. botulinum toxoid type D, a secreted bacterial endopeptidase that inhibits neurotransmitter release.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • Dot Blot
  • ELISA 1:100-1:2000
• Application Notes: Use in Dot blot reported in scientific literature (PMID:29396040).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.09% Sodium Azide
• Concentration: 28.9 mg/ml
• Purity: IgG purified

Alternate Names for Clostridium botulinum D Toxoid Antibody - BSA Free

• BoNT/D
• Bontoxilysin D
• BOTD
• Botulinum neurotoxin type D

Background

Clostridia are toxin-producing anaerobic bacteria that cause a number of serious diseases, including tetanus, botulism, and tissue infections. Clostridia normally inhabit the human intestinal tract, soil, and decaying vegetation. All species of clostridia produce toxins. Some clostridial diseases, such as botulism and the various diarrheal illnesses, result solely from the toxin without any bacterial invasion of tissue. In other clostridial diseases, such as tetanus and clostridial wound infections, there is both tissue invasion and toxin production.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Clostridium botulinum D Toxoid Antibody (NB100-62469)(1)

Publication using NB100-62469

• Zhang S, Lebreton F, Mansfield MJ et al. Identification of a botulinum neurotoxin-like toxin in a commensal strain of Enterococcus faecium Cell Host Microbe. 2018-01-26 [PMID: 29396040] (Cytometric Bead Assay Standard, Bacteria)