Clostridium Botulinum A Toxoid Antibody (KBA211) [DyLight 350]

Product Discontinued

Clostridium Botulinum A Toxoid Antibody (KBA211) [DyLight 350] Summary

• Immunogen: Hybridoma clone has been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with C. botulinum A toxoid.
• Specificity: C. botulinum A toxoid. Cross-reactivity in indirect ELISA: B toxoid (11.0 %) and E toxoid (49.0 %).
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Sandwich ELISA
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Bacteria.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Clostridium Botulinum A Toxoid Antibody (KBA211) [DyLight 350]

• Atx
• Bna
• BoNT/A
• Bontoxilysin A
• BotA
• BOTOX
• Botulinum neurotoxin type A
• Botulism A toxoid

Background

Clostridium botulinum neurotoxins are zinc-dependent proteases that block the release of acetylcholine from peripheral cholinergic nerve endings by targeting specific membrane proteins including synaptosomal-associated proteins (SNAP), vesicle-associated membrane proteins (VAMP), and syntaxins. Neurotoxin A is characteristically associated with human botulism and known to target and hydrolyse the 197-Gln-|-Arg-198 bond of SNAP-25.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.