Chlamydia Antibody (CF 6J12) [Janelia Fluor® 669]

• Reactivity: Ba
• Applications: WB, ELISA
• Clone: CF 6J12
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Janelia Fluor 669

Chlamydia Antibody (CF 6J12) [Janelia Fluor® 669] Summary

• Immunogen: Elementary bodies from C. trachomatis strain SAF2
• Specificity: NB100-64440 recognizes a genus specific epitope within Chlamydia lipopolysaccharide (LPS). LPS is a common feature of the outer envelope of gram negative bacteria, which acts as a potent endotoxin, triggering an innate immune response. Studies have shown however, that whilst the LPS of Chlamydia trachomatis does evoke an immune response, it displays only weak endotoxic activity when compared to that of other bacteria such as Salmonella Minnesota or Neisseria gonorrhoeae.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Predicted cross-reactivities: Chlamydophila sp.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Chlamydia Antibody (CF 6J12) [Janelia Fluor® 669]

• Chlamydia trachomatis

Background

Chlamydia trachomatis is an intracellular organism. Chlamydia usually infects the cervix and fallopian tubes of women and the urethra of men. Chlamydial infections are believed to be one of the most common of all STDs. It is generally thought that in a population of 15 million, there are up to 300,000 cases of chlamydia each year. Thus, there are many undiagnosed cases of chlamydia in the community. It has been estimated that the true prevalence of chlamydia in the sexually active population may be in the order of 5% to 10%. Chlamydia is one of the leading causes of blindness in underdeveloped countries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.