C4 Antibody (25.3e3) - BSA Free

Product Discontinued

C4 Antibody (25.3e3) - BSA Free Summary

• Immunogen: C4 isolated from human plasma adsorbed onto aluminum hydroxide gel.
• Specificity: Epitope specificity differs from that of NBP2-31554, as determined by inhibition ELISA.
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: C4
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: In Western blotting, the antibody reacts with C4, in reduced as well as non-reduced forms.
• Theoretical MW: 204 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 10mM Phosphate (pH 7.4) and 0.5M NaCl
• Preservative: 0.05% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A or G purified

Background

C4 is a component of the classical complement pathway and is split by activated C1s to C4a and C4b.Together C2a and C4b forms the classical C3 convertase. The molecular mass of C4 is 204 kDa and itconsists of 3 domains: alpha (97kDa), beta (75 kDa) and gamma (33 kDa).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: C4