BPDE Antibody (8E11) [Unconjugated]

Product Discontinued

BPDE Antibody (8E11) [Unconjugated] Summary

• Immunogen: BPDE-I-G coupled to BSA
• Specificity: The antibody recognizes both free polycyclic aromatic hydrocarbons (PAHs) and DNA adducts.
• Source: N/A
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified from ascites

Applications/Dilutions

• Dilutions:
  • Competitive ELISA

Packaging, Storage & Formulations

• Storage: Stored at -20 °C. For long term storage, freeze in working aliquots at -20 °C in a manual defrost freezer to avoid repeated freeze-thawings.
• Buffer: This antibody is provided from mouse ascites, provided at 1 mg/ml in PBS, 50% glycerol.
• Preservative: No Preservative

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for BPDE Antibody (8E11) [Unconjugated]

• Benzo Pyrene Dihydrodiol Epoxide
• BPDE

Background

The antibody may be used to investigate exposure to environmental and occupational pollutants. PAHs are released into the environment following incomplete combustion of organic materials. Human exposure to PAHs comes from various occupational, environmental, dietary and medicinal sources. Exposure to this group of compounds is believed to be carcinogenic.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for BPDE Antibody (4360-MC-100)(2)

Publications using 4360-MC-100

• J Hu, W Li, O Adebali, Y Yang, O Oztas, CP Selby, A Sancar Genome-wide mapping of nucleotide excision repair with XR-seq Nat Protoc, 2019-01-01;14(1):248-282. 2019-01-01 [PMID: 30552409] (Immunoprecipitation)
• Huang H, Chen G, Wang C, Lin Y, Liou S, Lai C, Wang S Exposure to heavy metals and polycyclic aromatic hydrocarbons and DNA damage in taiwanese traffic conductors. Cancer Epidemiol Biomarkers Prev, 2012-11-13;22(1):102-8. 2012-11-13 [PMID: 23150064]