Bacillus anthracis protective antigen Antibody (C3)

Product Discontinued

Bacillus anthracis protective antigen Antibody (C3) Summary

• Immunogen: Hybridoma clone has been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with highly purified protective antigen of Bacillus anthracis.
• Specificity: This is specific to the Protective antigen of Bacillus anthracis.This does not cross-react with lethal factor antigen of B. anthracis, Y. Pestis, F. Tularensis, Toxoplasma gondii.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Sandwich ELISA 1:100-1:2000
• Application Notes: Recommended pairs (capture-detection): NB100-73100 as capture with NB100-73102 or NB100-73103 as detection.

Reactivity Notes

Bacteria.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS (pH 7.4)
• Preservative: 0.09% Sodium Azide
• Purity: Protein A purified

Alternate Names for Bacillus anthracis protective antigen Antibody (C3)

• anthrax PA
• Anthrax toxins translocating protein
• PA 83
• PA
• PA83
• PAG
• Paga
• Protective antigen

Background

Anthrax toxins are composed of three distinct proteins, a protective antigen (PA), a lethal factor (LF) and an edema factor (EF). None of these proteins are toxic by themselves and several studies indicate that the anthrax toxin has the familiar A-B enzymatic binding structure, with PA acting as the binding domain and EF and/or LF acting as the active fragments.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.