Recombinant Avian Influenza A H7N9 Hemagglutinin (A/Anhui/1-BALF_RG45/2013) His Protein Summary
| Description |
A recombinant protein with a His-tag and corresponding to the amino acids 19-339 of Avian Influenza A H7N9 Hemagglutinin. Source: Baculovirus Amino Acid Sequence: ADL DKICLGH HAVSNGTKVN TLTERGVEVV NATETVERTN IPRICSKGKR TVDLGQCGLL GTITGPPQCD QFLEFSADLI IERREGSDVC YPGKFVNEEA LRQILRESGG IDKEAMGFTY SGIRTNGATS ACRRSGSSFY AEMKWLLSNT DNAAFPQMTK SYKNTRKSPA LIVWGIHHSV STAEQTKLYG SGNKLVTVGS SNYQQSFVPS PGARPQVNGL SGRIDFHWLM LNPNDTVTFS FNGAFIAPDR ASFLRGKSMG IQSGVQVDAN CEGDCYHSGG TIISNLPFQN IDSRAVGKCP RYVKQRSLLL ATGMKNVPEI PKGR |
| Source |
Baculovirus |
| Protein/Peptide Type |
Recombinant Protein |
| Purity |
>95%, by SDS-PAGE |
| Endotoxin Note |
< 1 EU per 1ug of protein (determined by LAL method) |
Applications/Dilutions
| Dilutions |
|
| Theoretical MW |
36 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Buffer |
PBS (pH 7.4), 10% glycerol |
| Preservative |
No Preservative |
| Concentration |
1 mg/ml |
| Purity |
>95%, by SDS-PAGE |
Alternate Names for Recombinant Avian Influenza A H7N9 Hemagglutinin (A/Anhui/1-BALF_RG45/2013) His Protein
Background
H7N9/HA (hemaggulutinin1) belongs to the influenza viruses hemagglutinin family. Influenza A virus subtype H7N9 (A/H7N9) is a bird flu strain of the species Influenza virus A Influenza and Influenza hemagglutinin (HA) or haemagglutinin is a type of hemagglutinin found on the surface of the influenza viruses. An H7N9 virus was first reported to have infected humans in March 2013, in China. The CDC estimates that the H7N9 virus has the greatest potential compared with other influenza A viruses to cause a pandemic, although the risk is low, because like other type A viruses, it is not easily transmitted between people in its current form. H7N9/HA is an antigenic glycoprotein and is responsible for binding the virus to the cell that is being infected. HA protein has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding of these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of host endosomal membrane with the viral membrane. Recombinant Influenza A virus (A/Anhui/1-BALF_RG45/2013(H7N9)) HA1 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are
guaranteed for 3 months from date of receipt.
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