Apoptosis Inducer Compounds Kit

Product Discontinued

Apoptosis Inducer Compounds Kit Summary

• Description: Five ready-to-use chemical reagents that induce apoptosis through different mechanisms. Set includes: Actinomycin D (10 mM), Camptothecin (2 mM), Cycloheximide (100 mM), Dexamethasone (10 mM), Etoposide (100 mM).
  
  This product is manufactured by Abcam and distributed by Novus Biologicals. (Abcam Catalog Number: ab102480)
• Kit Type: Kit

Packaging, Storage & Formulations

• Storage: Store at -20C.

Alternate Names for Apoptosis Inducer Compounds Kit

• Apoptosis Inducer Compounds

Background

Actinomycin D, an antineoplastic antibiotic, inhibits RNA synthesis. Camptothecin, an inhibitor of nuclear topoisomerase, induces apoptosis in many types of cells. Cycloheximide, an antibiotic against many yeast and fungi, inhibits protein synthesis. Dexamethasone, a highly stable glucocorticoid, probably induces apoptosis by binding and activating the intracellular glucocorticoid receptor. Etoposide, a derivative of podophyllotoxin, inhibits topoisomerase activity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Kits are guaranteed for 6 months from date of receipt.