15-deoxy-Delta 12, 14-PGJ2 ELISA Kit (Colorimetric) Summary
|Standard Curve Range
195 - 200,000 pg/ml
CV% < 14.4%
CV% < 6.2%
Tissue Culture Media - 97.4%
Human Saliva - 94.4%
Human Urine - 113.9%
Porcine Plasma - 105.0%
ELISA Kit (Colorimetric)
Packaging, Storage & Formulations
- Assay buffer
- GxR IgG Microtiter plate
- pNpp Substrate
- Stop solution
- Wash buffer
15-deoxy-12,14-Prostaglandin J2 (15-d-PGJ2) is one of the ultimate dehydration products of PGD2, formed via the intermediate 12-PGJ2. 15-d-PGJ2 is physiologically present in body fluids at concentration of 10-12 to 10-9 M, but increases dramatically under stress such as infection and inflammation. 15-d-PGJ2 exerts both pro- and anti-inflammatory effects in a cell-type and concentration-dependent manner, with many of these effects mediated via binding to the isoform of the peroxisome proliferators-activated receptor (PPAR-y). 15-d-PGJ2 appears to induce HO-1 expression by a PPAR-y-independent mechanism mediated by the generation of reactive oxygen species (ROS).
This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed
for 6 months from date of receipt.
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